Zocor - Simvastatin

Modified on 2009/10/14 21:33 by admin
Updated January 2008- Zocor, also known as simvastatin, is a cholesterol lowering medication manufactured by Merck & Co. Zocor belongs to the statin family of cholesterol drugs and is considered a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor.

Recently, another statin drug, Baycol, was removed from the market after causing at least 52 deaths. As a result, the safety of all statin drugs has subsequently come into question. While the Food and Drug Administration (FDA) maintains that Zocor causes considerably fewer adverse side effects than Baycol, the agency acknowledges that Zocor does pose some risk.

All statins increase a patient's chances of developing myositis and rhabdomyolysis, potentially fatal conditions that cause muscle pain and muscle deterioration and may lead to kidney failure. According to the FDA, the chances of developing myositis or rhabdomyolysis from Zocor are low. As such, Zocor remains on the market. See a licensed physician if you have concerns regarding the safety of Zocor, other statins, or any prescription drug. It should be noted that with the exception of Baycol, most doctors believe that the benefits of statin therapy outweigh the risks associated with this class of drugs.

Researchers have linked concurrent use of Serzone and Zocor to the development of rhabdomyolysis. A March 2003 article, written by physicians at the University of Cincinnati College of Medicine and published in John Hopkins University's Advanced Studies in Medicine, discussed three recent cases of rhabdomyolysis in patients who had undergone concomitant use of Serzone and Zocor.

January 2008

In 2008, results of a clinical trial of Zetia and Zocor, also known as Vytorin, were released that demonstrated no benefit to patients taking the drugs Zetia and Zocor. Patients took Zetia and Zocor in the form of Vytorin, which combines the prescription medication Zetia with Zocor. 

In the clinical trial of Vytorin, of which Zocor is a component drug, the results demonstrated that patients actually had worse fatty plaque growths in blood vessels than with Zocor alone.  Some of the participants in the clinical trial received Zetia in the form of Vytorin, and some took Zocor exclusively.  Those patients with high cholesterol taking Zocor exclusively actually fared better than those taking Vytorin.

September 2007

In 2007, the Institute for Safe Medication Practices and the Division of Public Health Sciences, Wake Forest University School of Medicine, conducted a longitudinal Adverse Events Reporting System Review of the U.S. FDA's most dangerous drugs. The study found Zocor to be one of the most dangerous drugs on the market with one of the highest numbers of adverse drug event reports.  Simvastatin was the fourteenth most dangerous drug, according to the FDA reports.  Over the eight years of the study, simvastatin was found to have caused over 3,800 events resulting in disability or serious incidents requiring medical treatment.

See your doctor if you are suffering from any side effects of simvastatin. In addition, it may be important to contact an attorney who can help you protect your legal rights. Please keep in mind that there may be time limits within which you must commence suit.

Attorneys associated with InjuryBoard.com will evaluate your case free of charge. In addition, you will not pay any fees or costs unless your attorney recovers money for you. Please click on the free Ask An Attorney button to take advantage of this valuable service.

See Also

  1. Cholesterol Drugs: Overview
  2. Fibromyalgia: Overview
  3. Kidney Failure
  4. Memory Loss
  5. Myositis: Overview
  6. Rhabdomyolysis
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