Soriatane / Acitretin

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Modified on 2009/10/14 21:33 by admin
Soriatane, also known as acitretin, belongs to a class of drugs known as retinoids and is indicated for the treatment of severe psoriasis, a debilitating skin disorder. Patients diagnosed with psoriasis suffer from inflamed, red, scaly lesions, caused when affected skin cells reproduce faster than normal. Soriatane allows skin to develop and grow normally by targeting receptors in skin cells. The drug, which comes in capsule form to be taken orally once a day, controls psoriasis but does not cure the disorder. Made by Roche, Soriatane was approved by the U.S. Food and Drug Administration in 1997.

Side effects of Soriatane use include, but may not be limited to, headache, nausea, joint and muscle pain, dry, irritated eyes, a runny or bloody nose, peeling, tingling skin, stomach pain, diarrhea, thinning of the hair and eyebrows, and mouth irritation.

A black box warning on Soriatane's label indicates that females who are pregnant or intend to become pregnant within three years of discontinuing treatment must not use the medication. Soriatane has been associated with an increased risk of birth defects. It is recommended that women use two or more reliable birth control treatments one month prior to treatment, during treatment and for at least three years after discontinuing treatment. The medication should be prescribed only after two negative pregnancy tests. If Soriatane is used with alcohol, a toxic compound may form which can also harm the fetus. Soriatane has been linked to liver damage and intercranial hypertension (pressure in the skull).

In May 2003, Roche added a warning to Soriatane's label, alerting users to the drug's link to depression, aggressive feelings and moods of self-harm. The new label is similar to that of Accutane, another retinoid that has been linked to depression.


See your doctor if you have suffered serious adverse side effects, including but not limited to severe depression, after taking Soriatane. In addition, it may be important to contact an attorney who can help you protect your legal rights. Please keep in mind that there may be time limits within which you must commence suit.



See Also

  1. Acne & Other Skin Disorder Drugs: Overview
  2. Birth Defects
  3. Depression: Overview
  4. Diarrhea: Overview
  5. Headaches
  6. Joints & Muscles: Overview
  7. Nausea: Overview
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