Factor VIII / Antihemophilic Factor (AHF)

Modified on 2009/10/14 21:42 by admin
Factor VIII, also known as antihemophilic factor or AHF, is indicated for the treatment of patients suffering from hemophilia A, an inherited disorder in which the blood clotting protein Factor VIII is deficient or abnormal. Affected persons are unable to form blood clots normally and therefore risk serious and life-threatening bleeding episodes. Replacement therapy with Factor VIII corrects the defect temporarily but must be given by intravenous infusion, in many cases daily or more often. Several pharmaceutical companies, including Bayer, Baxter, Aventis, Alpha and Armour Pharmaceutical sell a version of Factor VIII.

Side effects of Factor VIII include, but may not be limited to, headache, sore throat, upset stomach, nausea, dizziness, fatigue, fever, unusual bleeding and increased pulse rate.

In May 2003, The New York Times reported that several major drugmakers, including Bayer and Baxter, knowingly supplied hemophilia patients with Factor VIII, which is made from donated blood, even though many units were tainted with the HIV or hepatitis C virus. It is believed that thousands of patients from dozens of countries were exposed to the diseases from 1978 to 1990. In August 2003, seven Taiwanese patients who allege they developed HIV from tainted Factor VIII during the mid-1980s sued Bayer and Aventis. Bayer has been accused of selling a safer version of Factor VIII in the United States during this period while continuing to sell the high-risk version outside of the country.

See your doctor if you believe you developed HIV or hepatitis C because of Factor VIII. In addition, it may be important to contact an attorney who can help you protect your legal rights. Please keep in mind that there may be time limits within which you must commence suit.

See Also

  1. Blood Thinning Drugs: Overview
  2. AIDS & HIV: Overview
  3. Balance Problems: Overview
  4. Ear, Nose, & Throat Disorders
  5. Excessive Bleeding: Overview
  6. Fatigue: Overview
  7. Headaches
  8. Nausea: Overview
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