Antidepressants & Other Psychiatric Drugs

Modified on 2009/10/14 21:40 by admin
Ten percent of Americans will experience severe depression sometime during their lives. People who suffer from depression are often reluctant to admit their condition to friends and family. Additionally, these same friends and family members may not recognize the severity of the problem. For instance, your loved one may become angry with you for not "cheering up." He or she does not understand that your brain may function differently than normal and no matter how hard you try, you simply cannot "cheer up."

It is important to seek professional counseling and guidance from a medical doctor. There are many prescription medications for the treatment of depression and other emotional conditions. These drugs can turn your life around. Unfortunately, they can also have severe side effects, and some are more effective than others.

In December 2003, the U.K.'s Department of Health announced that all SSRI antidepressants, with the exception of Prozac, should not be prescribed to children under 18 because of their link to suicide. Medications facing a possible ban include Zoloft, Celexa, Lexapro and Luvox.

In March 2004, the Food and Drug Administration issued a Public Health Advisory that provides further cautions to physicians, their patients, and families and caregivers of patients about the need to closely monitor both adults and children with depression, especially at the beginning of treatment, or when the doses are changed with either an increase or decrease in the dose.

FDA is asking manufacturers to change the labels of ten drugs to include stronger cautions and warnings about the need to monitor patients for the worsening of depression and the emergence of suicidal ideation, regardless of the cause of such worsening.

The drugs under review include bupropion, citalopram, fluoxetine, fluvoxamine, mirtazapine, nefazodone, paroxetine, sertraline, escitalopram and venlafaxine. It should be noted that the only drug that has received approval for use in children with major depressive disorder is fluoxetine (Prozac). Several of these drugs are approved for the treatment of obsessive-compulsive disorder in pediatric patients, i.e., sertraline (Zoloft), fluoxetine (Prozac), and fluvoxamine (Luvox). Luvox is not approved as an antidepressant in the United States.

In September 2004, scientific advisers to the FDA asked the agency to add a black box label, the government's strongest warning for a medication, to all antidepressants due to their link to suicidal behavior in children. Advisers are recommending the addition of a pamphlet that details the warning signs of suicide and information on whether a child should be on an antidepressant. Parents may be asked to sign a form stating that they understand the potential risks of antidepressants. The FDA is not bound by the recommendations, but will take them into consideration when making a formal decision.

On October 15, 2004, the Food and Drug Administration issued a Public Health Advisory, asking manufacturers of all antidepressant drugs to revise the labeling for their products to include a boxed warning and expanded warning statements that alert health care providers to an increased risk of suicidality (suicidal thinking and behavior) in children and adolescents being treated with these agents, and additional information about the results of pediatric studies.

View sub-topics at right to learn more about some specific drugs used to treat emotional problems and some of the drugs' more serious adverse side effects.

See Also

  1. Abilify / Aripiprazole
  2. Adderall XR
  3. Ativan / Lorazepam
  4. Clozaril / Clozapine
  5. Cymbalta / Duloxetine
  6. Droleptan: Overview
  7. Prescription & Over-the-Counter Drugs: Overview
  8. Effexor / Venlafaxine Hydrochloride
  9. Geodon / Ziprasidone
  10. Mellaril / Thioridazine Hydrochloride: Overview
  11. Paxil / Paroxetine Hydrochloride
  12. Prozac / Fluoxetine Hydrochloride
  13. Remeron / Mirtazapine
  14. Risperdal / Risperidone
  15. Ritalin / Methylphenidate
  16. Serentil / Mesoridazine
  17. Seroquel / Quetiapine Fumarate
  18. Serzone / Nefazodone Hydrochloride
  19. St. John's Wort / Hypericum Perforatum
  20. Strattera
  21. Trilafon / Perphenazine
  22. Wellbutrin / Bupropion Hydrochloride
  23. Zoloft / Sertraline
  24. Zyban / Bupropion Hydrochloride
  25. Zyprexa / Olanzapine
  26. Depression: Overview
  27. Emotional Problems
  28. Hip Joint: Overview
  29. Mania: Overview
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